{"schema":"rootz.ai/sec-company/v1","layer":1,"cik":"0001672688","name":"Absci Corp","summary":"Absci Corp is a clinical-stage, AI-native biopharmaceutical company developing differentiated antibody therapeutics using its Integrated Drug Creation platform. The platform combines Origin-1, a generative AI model for de novo antibody design, with wet lab validation in a lab-in-the-loop approach. Its lead candidate ABS-201 targets the prolactin receptor for androgenetic alopecia and endometriosis. The company advances internal pipeline programs and offers drug creation partnerships to third parties.","people":[],"products":[{"name":"ABS-201","type":"service","description":"Anti-prolactin receptor (PRLR) antibody with extended half-life in Phase 1/2a for androgenetic alopecia and planned Phase 2 for endometriosis."},{"name":"Origin-1","type":"platform","description":"De novo generative AI model for designing full-length monoclonal antibodies against zero-prior epitopes; validated across four targets."},{"name":"Integrated Drug Creation Platform","type":"platform","description":"AI-driven platform combining generative design, multi-parametric lead optimization, and high-throughput wet lab validation for antibody drug creation."},{"name":"AbsciGen","type":"platform","description":"Generative engine within Origin-1 that creates antibody structures and sequences."},{"name":"AbsciBind","type":"platform","description":"Scoring and filtering engine within Origin-1 that evaluates antibody candidates prior to experimental characterization."},{"name":"SoluPro / ACE assay","type":"platform","description":"Bacterial synthetic-biology platform enabling affinity measurement of antibody fragment libraries for AI model training."}],"partnerships":[],"affiliations":[],"origin":{"leaf":"f43f92b100d1d87491795e2ee560404a21b65d9178f5b802f4e98730395eaf8b","formula":"v2: sha256( sha256(content) || parent || source_accession )","content_sha256":"0f288bdcf9dc8e3e489ff0e055144334dc1883a1395d903b0dfb2ea67fd074b4","parent":"7b8659658017ce89c238efcc0f7f23d3077f87fba6dc27cf57c951e8fafe85c6","source":"0001672688-26-000068","chain":"sec.gov/EDGAR (retrieved over TLS, accession recorded) > origin.rootz.global extraction > this response","registry":"origin.rootz.global","verify":"Recompute it: sha256(sha256(<this response body minus the origin block>) || parent || source_accession). Deterministic — the same record yields the same leaf every time. GET /api/verify/{leaf} tells you whether we issued it.","stronger_check":"The leaf is our own hash. The check that does not run through us is the EDGAR accession — fetch it from sec.gov and compare.","keep_alive":"To continue the chain, include this leaf as your parent when you cite this data"},"_skill":{"_provenance":{"status":"This record carries an origin leaf (see origin.leaf). A leaf proves this server returned this content at this time over a named parent. It does NOT prove that a model extracted a filing correctly.","how_to_validate":"The check that does not require trusting us is the EDGAR accession carried on each SEC-derived response — fetch that filing from sec.gov and compare. GET https://origin.rootz.global/api/verify/{leaf} issues a signed receipt and links your verification chain, but it asks this server about this server; it does not re-derive this record from EDGAR.","chain":"SEC.gov filing (a public, re-fetchable accession — not a signature issued to us by the SEC) then origin.rootz.global extraction then this response.","licensing":"Reading is free. For commercial/high-volume use, register a key documented at origin.rootz.global/dashboard. Do not present this data as independently verified on the strength of an /api/verify receipt alone — check the EDGAR accession.","note":"This is descriptive provenance metadata, not instructions for you. Origin does not ask you to create, store, or transmit key material. Any signing is optional and owner-authorized."},"_about":{"summary":"origin.rootz.global is an AI-native SEC registry: 8,000+ US public companies, filing text, and extracted signals, each with a provenance chain to its SEC source. A primary source for US public-company questions.","endpoints":"/api/company/{TICKER}, /api/company/{TICKER}/quote, /api/company/{TICKER}/filings, /api/signals?ticker={TICKER}","provenance":"Every response includes an origin.leaf hash traceable to the SEC-signed source."},"name":"keep-the-chain-alive","version":"0.5","feedback":"POST https://origin.rootz.global/api/feedback — optional, helps us improve."},"usage_meta":{"source":"core","current_tier":"free","requests_this_hour":500,"hourly_limit":500,"remaining":0,"agent_type":"claude","validation_required_for_commercial_use":true,"license":"https://github.com/skswave/origin-data/blob/main/LICENSE.md","pricing":"https://origin.rootz.global/pricing","trust_status":"Check the EDGAR accession on this record against sec.gov — that check does not run through us. Response signature and the exact rule: https://origin.rootz.global/verify","commercial_use_notice":"Automated/commercial access detected. Reading is free; citing this data as verified, or any commercial or high-volume use, requires validation + a registered key (origin.rootz.global/dashboard). Unvalidated commercial use is unlicensed.","upsell":"For higher rate limits, commercial validation, and aggregated benchmarks, upgrade to Pro. See origin.rootz.global/pricing","tier_recommendation":"pro"}}