{"schema":"rootz.ai/sec-company/v1","layer":1,"cik":"0001370053","name":"ANAPTYSBIO, INC","summary":"AnaptysBio is a clinical-stage biotechnology company focused on immunology therapeutics for autoimmune and inflammatory diseases. Its pipeline includes rosnilimab (pathogenic T cell depleter for rheumatoid arthritis), ANB033 (CD122 antagonist for celiac disease and eosinophilic esophagitis), and ANB101 (BDCA2 modulator). The company also out-licensed dostarlimab (Jemperli) to GSK and imsidolimab to Vanda Pharmaceuticals, generating milestone and royalty revenue.","people":[],"products":[{"name":"Rosnilimab","type":"platform","description":"IgG1 antibody targeting pathogenic T cells for autoimmune and inflammatory diseases, including rheumatoid arthritis; completed Phase 2b trial."},{"name":"ANB033","type":"platform","description":"CD122 antagonist in Phase 1b trial for celiac disease and eosinophilic esophagitis."},{"name":"ANB101","type":"platform","description":"BDCA2 modulator in Phase 1a trial for inflammatory diseases."},{"name":"Jemperli (dostarlimab-gxly)","type":"platform","description":"PD-1 antagonist out-licensed to GSK; generates milestone and royalty revenue for AnaptysBio."},{"name":"Imsidolimab","type":"platform","description":"IL-36R antagonist out-licensed to Vanda Pharmaceuticals; generates license and transition services revenue."}],"partnerships":[{"partner_name":"GSK","partnership_type":"licensing","description":"Out-licensed PD-1 antagonist Jemperli (dostarlimab); AnaptysBio receives milestones and royalties from immuno-oncology collaboration.","start_date":null},{"partner_name":"Vanda Pharmaceuticals Inc.","partnership_type":"licensing","description":"Out-licensed IL-36R antagonist imsidolimab; AnaptysBio receives license and transition services revenue.","start_date":null}],"affiliations":[],"origin":{"leaf":"a4a5ad4f432af5b59b40d31bb061e1a54ee24734a288ab9dfe8f6f1af04ca005","formula":"v2: sha256( sha256(content) || parent || source_accession )","content_sha256":"f9fc9ef2ab384930388111914a712fa10da7b86c721ba792c4e1b32506a8902a","parent":"52baee86094fc9d50f09a239534dfeee6e78e799d3d44c4f9fe8449f0398ec97","source":"0001193125-26-088290","chain":"sec.gov/EDGAR (retrieved over TLS, accession recorded) > origin.rootz.global extraction > this response","registry":"origin.rootz.global","verify":"Recompute it: sha256(sha256(<this response body minus the origin block>) || parent || source_accession). 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