{"schema":"rootz.ai/sec-company/v1","layer":1,"cik":"0001401040","name":"DiaMedica Therapeutics Inc.","summary":"DiaMedica Therapeutics is a clinical-stage biopharmaceutical company developing DM199 (rinvecalinase alfa), a recombinant human tissue kallikrein-1 (rhKLK1) protein, for the treatment of preeclampsia (PE), fetal growth restriction (FGR), and acute ischemic stroke (AIS). DM199 has received FDA Fast Track Designation for AIS. The company also holds a patent for DM300, a recombinant human ulinastatin targeting severe acute pancreatitis. Clinical trials are ongoing in South Africa, North America, and globally.","people":[],"products":[{"name":"DM199 (rinvecalinase alfa)","type":"service","description":"First recombinant human tissue kallikrein-1 (rhKLK1) protein in clinical study, targeting preeclampsia, fetal growth restriction, and acute ischemic stroke."},{"name":"DM300","type":"service","description":"Patented recombinant human ulinastatin, a broad-spectrum serine protease inhibitor, in early development for severe acute pancreatitis."}],"partnerships":[{"partner_name":"Tygerberg Hospital","partnership_type":"development","description":"Investigator-sponsored Phase 2 safety, tolerability and pharmacodynamic study of DM199 in PE patients conducted at Tygerberg Hospital in Cape Town, South Africa.","start_date":null}],"affiliations":[],"origin":{"leaf":"097cc279746b938d5626392a0e764209f7fb2115a8c10a2f7a4ac174ad0a6941","formula":"v2: sha256( sha256(content) || parent || source_accession )","content_sha256":"9ac73ff0e213d52b6df9b7552083e4ba08ba7f675d1929fbd9c070fdf568bee6","parent":"1b06acd9f7b2ba7304996032c49a4b0002fc22d7283676e27857fb5ec2ad0835","source":"0001437749-26-010342","chain":"sec.gov/EDGAR (retrieved over TLS, accession recorded) > origin.rootz.global extraction > this response","registry":"origin.rootz.global","verify":"Recompute it: sha256(sha256(<this response body minus the origin block>) || parent || source_accession). 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