{"schema":"rootz.ai/sec-company/v1","layer":1,"cik":"0000818033","name":"HERON THERAPEUTICS, INC. /DE/","summary":"Heron Therapeutics is a commercial-stage biotechnology company focused on acute care and oncology. Its portfolio includes ZYNRELEF (dual-acting local anesthetic for postoperative pain), APONVIE (IV aprepitant for postoperative nausea and vomiting), CINVANTI (IV aprepitant for chemotherapy-induced nausea and vomiting), and SUSTOL (extended-release injectable granisetron for chemotherapy-induced nausea and vomiting). The company uses its proprietary Biochronomer Technology for sustained drug delivery and commercializes products through a U.S.-based sales force of 78 employees.","people":[],"products":[{"name":"ZYNRELEF","type":"hardware","description":"Fixed-dose combination of bupivacaine and meloxicam; extended-release local anesthetic for postoperative pain up to 72 hours after soft tissue and orthopedic surgeries."},{"name":"APONVIE","type":"hardware","description":"First IV formulation of aprepitant (NK1 receptor antagonist) for prevention of postoperative nausea and vomiting in adults via single 30-second IV injection."},{"name":"CINVANTI","type":"hardware","description":"IV formulation of aprepitant, free of synthetic surfactants, indicated for prevention of acute and delayed nausea and vomiting associated with HEC and MEC chemotherapy."},{"name":"SUSTOL","type":"hardware","description":"Extended-release injectable 5-HT3 receptor antagonist using Biochronomer Technology, maintaining therapeutic granisetron levels for 5 days; indicated for MEC and AC chemotherapy regimens."}],"partnerships":[{"partner_name":"Crosslink Network","partnership_type":"strategic","description":"Co-promotion agreement entered January 2024; Crosslink Network is lead U.S. partner for ZYNRELEF promotion for orthopedic indications.","start_date":null}],"affiliations":[],"origin":{"leaf":"f60d08e4fe58b70897fb7d220a7e0cfc5f7720d360c4ecedf109afabc03d832b","formula":"v2: sha256( sha256(content) || parent || source_accession )","content_sha256":"98e7b279e4b19821fe3277a2c02fe12bc3abe64f3c51c14888b5a80e8f58b5e4","parent":"a69d89fba8e39ce28bb37fc530fe9486b77b6da2b8aebcf4ceb1f21ec43226f4","source":"0001193125-26-073515","chain":"sec.gov/EDGAR (retrieved over TLS, accession recorded) > origin.rootz.global extraction > this response","registry":"origin.rootz.global","verify":"Recompute it: sha256(sha256(<this response body minus the origin block>) || parent || source_accession). 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