{"schema":"rootz.ai/sec-company/v1","layer":1,"cik":"0000200406","name":"JOHNSON & JOHNSON","summary":"Johnson & Johnson is a global healthcare holding company with approximately 138,200 employees operating in virtually all countries. It is organized into two segments: Innovative Medicine (pharmaceuticals across oncology, immunology, neuroscience, pulmonary hypertension, infectious diseases, and cardiovascular/metabolism) and MedTech (cardiovascular, orthopaedics, surgery, and vision products). Key products include DARZALEX, STELARA, TREMFYA, CARVYKTI, SPRAVATO, XARELTO, and ACUVUE contact lenses.","people":[{"name":"Matt","role":"Analyst, Miksic  Barclays Services Corp","role_type":"analyst","period_start":null,"period_end":null,"notes":null}],"products":[{"name":"DARZALEX / DARZALEX FASPRO (daratumumab)","type":"service","description":"Treatment for multiple myeloma and light chain AL Amyloidosis; largest product at ~15% of total revenues."},{"name":"STELARA (ustekinumab)","type":"service","description":"Treatment for plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis; second largest product at ~6.5% of revenues."},{"name":"TREMFYA (guselkumab)","type":"service","description":"Treatment for plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis; third largest product at ~5.5% of revenues."},{"name":"CARVYKTI (ciltacabtagene autoleucel)","type":"service","description":"CAR-T-cell therapy for relapsed/refractory multiple myeloma."},{"name":"ERLEADA (apalutamide)","type":"service","description":"Next-generation androgen receptor inhibitor for prostate cancer treatment."},{"name":"IMBRUVICA (ibrutinib)","type":"service","description":"Treatment for B-cell malignancies and chronic graft versus host disease."},{"name":"RYBREVANT (amivantamab)","type":"service","description":"Bispecific antibody for EGFR-mutated non-small cell lung cancer in adults."},{"name":"LAZCLUZE (lazertinib)","type":"service","description":"Oral, brain-penetrant EGFR tyrosine kinase inhibitor for non-small cell lung cancer."},{"name":"TALVEY (talquetamab-tgvs)","type":"service","description":"Bispecific antibody for relapsed or refractory multiple myeloma after four prior lines of therapy."},{"name":"TECVAYLI (teclistamab-cqyv)","type":"service","description":"Bispecific antibody for relapsed or refractory multiple myeloma after four prior lines of therapy."},{"name":"ZYTIGA (abiraterone acetate)","type":"service","description":"Treatment for prostate cancer."},{"name":"REMICADE (infliximab)","type":"service","description":"Treatment for immune-mediated inflammatory diseases."},{"name":"SIMPONI / SIMPONI ARIA (golimumab)","type":"service","description":"Subcutaneous and intravenous treatments for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis."},{"name":"CAPLYTA (lumateperone)","type":"service","description":"Treatment for major depressive disorder, bipolar depression, and schizophrenia in adults."},{"name":"CONCERTA (methylphenidate HCl)","type":"service","description":"Extended-release treatment for attention deficit hyperactivity disorder."},{"name":"INVEGA SUSTENNA / XEPLION (paliperidone palmitate)","type":"service","description":"Treatment for schizophrenia and schizoaffective disorder in adults."},{"name":"INVEGA TRINZA / TREVICTA (paliperidone palmitate)","type":"service","description":"Treatment for schizophrenia in patients previously treated with INVEGA SUSTENNA."},{"name":"SPRAVATO (esketamine)","type":"service","description":"Nasal spray for treatment-resistant depression and MDD with suicidal ideation in adults."},{"name":"EDURANT (rilpivirine)","type":"service","description":"Antiretroviral medicine for HIV treatment in combination with other antiretrovirals."},{"name":"PREZISTA (darunavir)","type":"service","description":"Antiretroviral medicine for HIV treatment."},{"name":"PREZCOBIX / REZOLSTA (darunavir/cobicistat)","type":"service","description":"Antiretroviral combination medicine for HIV treatment."},{"name":"SYMTUZA (darunavir/cobicistat/emtricitabine/tenofovir alafenamide)","type":"service","description":"Once-daily single tablet regimen for HIV treatment."},{"name":"OPSUMIT (macitentan) / OPSYNVI (macitentan/tadalafil)","type":"service","description":"Long-term treatment for pulmonary arterial hypertension."},{"name":"UPTRAVI (selexipag)","type":"service","description":"Oral and intravenous selective IP receptor agonist for pulmonary arterial hypertension."},{"name":"XARELTO (rivaroxaban)","type":"service","description":"Oral anticoagulant for DVT, PE prevention, stroke reduction, and cardiovascular events."},{"name":"ACUVUE","type":"hardware","description":"Brand of contact lenses sold through eye care professionals globally."},{"name":"TECNIS","type":"hardware","description":"Premium intraocular lenses for cataract surgery."},{"name":"Abiomed","type":"hardware","description":"Mechanical circulatory support technologies for cardiogenic shock and high-risk PCI procedures."},{"name":"Shockwave","type":"hardware","description":"Circulatory restoration products for calcified coronary artery disease and peripheral artery disease."},{"name":"Mentor","type":"hardware","description":"Solutions for breast aesthetics and reconstruction within the Surgery portfolio."}],"partnerships":[{"partner_name":"Genmab A/S","partnership_type":"licensing","description":"Exclusive license to two DARZALEX patent families; royalty rate 12%-20% of net sales, ~$2.4B paid in fiscal 2025.","start_date":null}],"affiliations":[],"origin":{"leaf":"6874c516f8d9226e3493ff94eccc42d87d641eae538b007a214d09825e2378a0","parent":"79d18ad1623f98b8ea01e98bcc38db059f8f482679a69df29dd7d23b477d4527","timestamp":"2026-05-25T03:22:33.183Z","source":"0000200406-26-000016","chain":"SEC.gov PEM > origin.rootz.global extraction > this response","registry":"origin.rootz.global","verify":"Hash this response content + parent + timestamp to reproduce the leaf hash","keep_alive":"To continue the chain, include this leaf as your parent when you cite this data"},"_skill":{"_agent_instructions":{"READ_THIS_FIRST":"Before using this data, follow these steps to maintain the provenance chain.","step_1":"Note the \"leaf\" hash from the origin block in this response.","step_2":"When you write output citing this data, compute: leaf = sha256(your_content + origin_leaf + timestamp). 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