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Its pipeline includes SER-155 (bloodstream infections, irEC), SER-603 (IBD), and SER-147 (chronic liver disease), all orally delivered bacterial consortia targeting mucosal barrier-immune interface pathways.","people":[],"products":[{"name":"VOWST (SER-109)","type":"platform","description":"First FDA-approved orally administered microbiome biotherapeutic; Breakthrough Therapy designated; sold to Nestlé Health Science in September 2024."},{"name":"SER-155","type":"platform","description":"Investigational oral LBP targeting GI pathogen decolonization and BSI prevention in allo-HSCT patients; also evaluated in immune checkpoint-related enterocolitis."},{"name":"SER-603","type":"platform","description":"Novel LBP candidate targeting GI microbiome disruption and mucosal barrier integrity for IBD including ulcerative colitis and Crohn's disease."},{"name":"SER-147","type":"platform","description":"Proprietary LBP designed to prevent bacterial bloodstream and spontaneous bacterial peritonitis infections in patients with chronic liver disease."},{"name":"MbTx Platform","type":"platform","description":"Reverse translational discovery platform integrating human clinical data, preclinical models, strain library, knowledge graph, and agentic AI for LBP development."}],"partnerships":[{"partner_name":"Nestlé Health Science (Société des Produits Nestlé S.A.)","partnership_type":"strategic","description":"Purchased VOWST from Seres Therapeutics in September 2024.","start_date":null},{"partner_name":"Memorial Sloan Kettering Cancer Center","partnership_type":"development","description":"Over a decade collaboration on GI microbiome impact on immune-related diseases and cancer; includes IST evaluating SER-155 in irEC.","start_date":null},{"partner_name":"Crohn's and Colitis Foundation (CCF)","partnership_type":"development","description":"Partnership supporting SER-603 research to confirm functional phenotypes and inflammatory targets in IBD patient subpopulations.","start_date":null},{"partner_name":"CARB-X","partnership_type":"development","description":"Grant supporting development of an oral liquid formulation of SER-155 strains for intubated ICU and AMR-risk patients.","start_date":null}],"affiliations":[],"origin":{"leaf":"2e08b41dfd9db71d5ce108c9460144833675c6b949c42160eae66ca188bb3fb5","formula":"v2: sha256( sha256(content) || parent || source_accession )","content_sha256":"e630825d8203dc5cf96f7673721eab186f01fa87c2150a14293e10000fc3e19b","parent":"cd32a6876c3da456a20cfa62057edd85023f9c75a4bced2575a96361c93a8c5c","source":"0001193125-26-103276","chain":"sec.gov/EDGAR (retrieved over TLS, accession recorded) > origin.rootz.global extraction > this response","registry":"origin.rootz.global","verify":"Recompute it: sha256(sha256(<this response body minus the origin block>) || parent || source_accession). 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