{"schema":"rootz.ai/sec-company/v1","layer":1,"cik":"0001604821","name":"Natera, Inc.","summary":"Natera, Inc. is a diagnostics company using proprietary cell-free DNA (cfDNA) technology combining molecular assays and bioinformatics algorithms to detect genetic variations. It operates in three segments: oncology (Signatera ctDNA MRD test, Altera CGP, Latitude), women's health (Panorama NIPT, hereditary cancer screening via Empower), and organ health (transplant rejection and kidney disease testing). Revenues were $2,306.1 million in 2025, processing approximately 3.5 million tests. Headquartered in Austin, Texas.","people":[],"products":[{"name":"Signatera","type":"service","description":"Personalized ctDNA blood test for MRD assessment, recurrence monitoring, and treatment response evaluation in cancer patients."},{"name":"Latitude","type":"service","description":"Blood-based MRD test for colorectal cancer that does not require a tumor tissue sample."},{"name":"Altera","type":"service","description":"Tissue-based comprehensive genomic profiling test identifying genomic alterations and biomarkers for therapy selection."},{"name":"Empower","type":"service","description":"Hereditary cancer screening test offering five panel options across 12 cancer types with over 190 gene options."},{"name":"Panorama","type":"service","description":"Non-invasive prenatal test (NIPT) launched in 2013, screening for fetal aneuploidies, microdeletions, and inherited genetic conditions."},{"name":"Constellation","type":"platform","description":"Cloud software platform enabling laboratories worldwide to run Natera tests locally and access algorithms remotely."}],"partnerships":[{"partner_name":"Global laboratory and distribution partners (100+)","partnership_type":"strategic","description":"Network of over 100 international laboratory and distribution partners, including several of the largest international laboratories.","start_date":null},{"partner_name":"NIH National Cancer Institute","partnership_type":"development","description":"Collaboration to generate clinical validity and utility data for Signatera across multiple cancer types.","start_date":null},{"partner_name":"Pharmaceutical companies","partnership_type":"development","description":"Research use partnerships with biopharmaceutical companies for Signatera ctDNA testing in oncology research.","start_date":null}],"affiliations":[],"origin":{"leaf":"e53fef275acf87f8b369cdf987372320c1c56b3bc5b80187038ede2f7bfce5a3","formula":"v2: sha256( sha256(content) || parent || source_accession )","content_sha256":"b49a0d3382cca3f6040079a8352d39929fdf8ea059ebfbdb1e5361c80afb8885","parent":"c950f7b0eb4b2e3978a46118e8a08c457a293856a2dd635ba792ef053e1faf32","source":"0001104659-26-020881","chain":"sec.gov/EDGAR (retrieved over TLS, accession recorded) > origin.rootz.global extraction > this response","registry":"origin.rootz.global","verify":"Recompute it: sha256(sha256(<this response body minus the origin block>) || parent || source_accession). 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