{"schema":"rootz.ai/sec-company/v1","layer":1,"cik":"0001415397","name":"Raphael Pharmaceutical Inc.","summary":"Raphael Pharmaceutical Inc. is a pharmaceutical research and development company focused on cannabinoid-based drug therapies, including CBD oil. Its lead product candidate targets rheumatoid arthritis (RA), with a proof-of-concept clinical study completed in December 2024. The company also develops candidates for asthma and COVID-19, and launched RaphaWell, a dietary supplement for RA support, under IRB-approved clinical testing in the U.S.","people":[],"products":[{"name":"Raphael's Formula / RaphaWell","type":"platform","description":"Proprietary cannabinoid-based natural formula launched as a dietary supplement for RA symptom support, clinically tested under IRB approval."},{"name":"RA Product Candidate","type":"platform","description":"Cannabinoid-based pharmaceutical drug candidate for treatment of rheumatoid arthritis, targeting IND submission to FDA and MOH."},{"name":"Asthma Product Candidate","type":"platform","description":"Pre-clinical stage cannabinoid-based drug candidate for asthma treatment, leveraging COVID-19 research insights."},{"name":"COVID-19 Product Candidate","type":"platform","description":"Cannabis-based drug candidate to alleviate deterioration in COVID-19 patients; MOH clinical trial proposal accepted March 2023."}],"partnerships":[{"partner_name":"Rambam Med-Tech Ltd. (Rambam Health Care Campus)","partnership_type":"development","description":"Conducted pre-clinical studies on human-derived immune cells and mouse models for RA, COVID-19, and asthma candidates.","start_date":null},{"partner_name":"Medical Cannabis Research and Innovation Center at Rambam","partnership_type":"development","description":"October 2022 agreement to develop a patentable cannabinoid formulation for rheumatoid diseases; co-filed provisional patent in November 2025.","start_date":null},{"partner_name":"MindMate, Inc. dba Citruslabs","partnership_type":"development","description":"Managed the U.S. proof-of-concept clinical study for the RA product candidate conducted in Santa Monica, California.","start_date":null}],"affiliations":[],"origin":{"leaf":"f005dcbcfae522afe0b1adb3fc5e615cdde161867c0a8e3071bb0f6e5d0ebe72","formula":"v2: sha256( sha256(content) || parent || source_accession )","content_sha256":"39c082c39c94496f109bfeb4b5489096555727097eeacdd2991dec4b67cee22f","parent":"7c3c5554ca800a45e420fb564f028b8f85f0e464c57da444cbffeef147fe9b8e","source":"0001213900-26-037402","chain":"sec.gov/EDGAR (retrieved over TLS, accession recorded) > origin.rootz.global extraction > this response","registry":"origin.rootz.global","verify":"Recompute it: sha256(sha256(<this response body minus the origin block>) || parent || source_accession). 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