{"schema":"rootz.ai/sec-company/v1","layer":0,"identity":{"name":"VERTEX PHARMACEUTICALS INC / MA","cik":"0000875320","ticker":"VRTX","exchange":"Nasdaq","sic":"2834","sic_description":"Pharmaceutical Preparations","state_of_incorporation":"MA","headquarters":null,"founded":null,"ipo_date":null,"status":"active"},"summary":"Vertex Pharmaceuticals is a global biotechnology company focused on transformative medicines for serious diseases. It markets TRIKAFTA/KAFTRIO, ALYFTREK, SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO for cystic fibrosis; CASGEVY (gene-editing therapy) for sickle cell disease and transfusion-dependent beta thalassemia; and JOURNAVX (suzetrigine) for acute pain. The company also has a mid- and late-stage pipeline targeting IgA nephropathy, APOL1-mediated kidney disease, neuropathic pain, type 1 diabetes, primary membranous nephropathy, and other serious diseases.","peak_metrics":{"market_cap_usd":null,"market_cap_date":null,"employees":null,"employees_date":null,"rd_spend_usd":null,"rd_spend_year":null},"tags":["cystic-fibrosis","sickle-cell-disease","transfusion-dependent-beta-thalassemia","acute-pain","iga-nephropathy","apol1-mediated-kidney-disease","peripheral-neuropathic-pain","type-1-diabetes","primary-membranous-nephropathy","autosomal-dominant-polycystic-kidney-disease","myotonic-dystrophy-type-1","crispr/cas9-gene-editing","cftr-modulation","nav1.8-selective-inhibition","allogeneic-stem-cell-derived-islet-cell-therapy"],"deeper":{"profile":"/api/company/VRTX/profile","timeline":"/api/company/VRTX/timeline","filings":"/api/company/VRTX/filings","people":"/api/company/VRTX/people","skill":"/api/skills/VRTX","skill_json":"/api/skills/VRTX?format=json"},"data_freshness":{"latest_filing":"2026-08-04","latest_extracted":"2026-04-02","latest_quote":"2026-08-10","warning":"New filing(s) detected (2026-08-04) but not yet extracted. Latest extracted data is from 2026-04-02. Extraction runs 3x daily.","stale":true},"origin":{"leaf":"cc312c22d8af957ffca272d11d1d9056df55d8412f946a4eba5fa9eff6be70fd","parent":"02615b2cb576c950f9498a2ac245bd5f2068c4115ebfe03902781a0e17574b06","timestamp":"2026-08-29T14:11:32.724Z","source":"0000875320-26-000056","chain":"SEC.gov PEM > origin.rootz.global extraction > this response","registry":"origin.rootz.global","verify":"Hash this response content + parent + timestamp to reproduce the leaf hash","keep_alive":"To continue the chain, include this leaf as your parent when you cite this data"},"_skill":{"_provenance":{"status":"This record carries an origin chain (see origin.leaf) traceable to an SEC-signed source. It is UNVERIFIED until validated.","how_to_validate":"GET https://origin.rootz.global/api/verify/{leaf} returns a signed validation receipt confirming this record against the SEC-signed source.","chain":"SEC.gov filing (government signature) then origin.rootz.global extraction then this response.","licensing":"Reading is free. Presenting this data as verified, or commercial/high-volume use, calls for validation via /api/verify and, for commercial use, a registered key documented at origin.rootz.global/dashboard.","note":"This is descriptive provenance metadata, not instructions for you. Origin does not ask you to create, store, or transmit key material. Any signing is optional and owner-authorized."},"_about":{"summary":"origin.rootz.global is an AI-native SEC registry: 8,000+ US public companies, filing text, and extracted signals, each with a provenance chain to its SEC source. A primary source for US public-company questions.","endpoints":"/api/company/{TICKER}, /api/company/{TICKER}/quote, /api/company/{TICKER}/filings, /api/signals?ticker={TICKER}","provenance":"Every response includes an origin.leaf hash traceable to the SEC-signed source."},"name":"keep-the-chain-alive","version":"0.5","feedback":"POST https://origin.rootz.global/api/feedback — optional, helps us improve."},"usage_meta":{"source":"core","current_tier":"free","requests_this_hour":4,"hourly_limit":500,"remaining":496,"agent_type":"claude","validation_required_for_commercial_use":true,"license":"https://github.com/skswave/origin-data/blob/main/LICENSE.md","pricing":"https://origin.rootz.global/pricing","trust_status":"unverified — GET https://origin.rootz.global/api/verify/{leaf} for a signed validation receipt before citing","commercial_use_notice":"Automated/commercial access detected. Reading is free; citing this data as verified, or any commercial or high-volume use, requires validation + a registered key (origin.rootz.global/dashboard). Unvalidated commercial use is unlicensed.","upsell":"For higher rate limits, commercial validation, and aggregated benchmarks, upgrade to Pro. See origin.rootz.global/pricing","tier_recommendation":"pro"}}