NORTHWEST BIOTHERAPEUTICS INC

NWBO | OTC | CIK: 0001072379 | SIC: 2834 Pharmaceutical Preparations | active
Northwest Biotherapeutics is a biotechnology company developing personalized immune therapies for cancer using its DCVax platform technology. DCVax uses activated dendritic cells to mobilize a patient's own immune system against cancer. Its lead product, DCVax-L, targets operable solid tumors including glioblastoma multiforme (GBM). The company completed a 331-patient Phase III trial for GBM, published results in JAMA Oncology, and submitted a Marketing Authorization Application in the U.K. in December 2023.
oncologyimmuno-oncologycell-therapybrain-cancer-(glioblastoma-multiforme)solid-tumor-cancers
AI agents: Get this data as structured JSON (~200 tokens):
https://origin.rootz.global/api/company/NWBO
Profile | Timeline | SEC Filings | People

Products

NameTypeDescription
DCVax-LplatformPersonalized dendritic cell immunotherapy for solid tumor cancers where the tumor can be surgically removed; lead candidate in Phase III for glioblastoma multiforme.
DCVax-DirectplatformPersonalized dendritic cell immunotherapy designed to treat inoperable solid tumors via direct injection; completed 40-patient Phase I trial.
Flaskworks SystemhardwareAutomated closed manufacturing system for DCVax-L production, designed to enable scale-up for commercial operations.

Partnerships

PartnerTypeDescription
Advent BioServicesdevelopmentContract manufacturer and operator of the Sawston, U.K. manufacturing facility; subleases space and conducts qualification and validation activities.
Northeastern UniversitylicensingExclusively licensed patents and patent applications related to automated cell culture systems to Flaskworks subsidiary.
Cambridge Development AuthoritystrategicProvided a buildout loan for the Sawston facility, with an obligation for the facility to benefit the regional business ecosystem.

SEC Filings

View all SEC EDGAR filings: EDGAR Company Page

Structured filing index: /api/company/NWBO/filings

Origin — Data Provenance
This profile was extracted from SEC EDGAR filings (PEM-signed by sec.gov).
Every API response includes a cryptographic origin leaf for chain-of-custody tracking.
AI Discovery Document | Registry Metrics | GitHub