CKDXF · OTC · SIC 2836: Biological Products, (No Diagnostic Substances)
165
SEC Filings
$0.01
Close 2026-06-08
Business Summary
Opthea Ltd is a clinical-stage biopharmaceutical company that developed sozinibercept (OPT-302), a VEGF-C/VEGF-D inhibitor previously administered via intravitreal injection for wet age-related macular degeneration (AMD). After Phase 3 trials (COAST and ShORe) failed to meet primary endpoints in March 2025, the company discontinued sozinibercept development and is now conducting a strategic review focused on reformulating VEGF-C/VEGF-D targeting drug candidates for delivery to other organs.
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