Aptevo Therapeutics Inc. is a clinical-stage biotechnology company focused on developing novel immunotherapy candidates for cancer treatment. The company operates two proprietary platforms, ADAPTIR and ADAPTIR-FLEX, for designing multi-specific antibody candidates. Its pipeline includes two clinical candidates—mipletamig (CD123xCD3 bispecific for AML) and ALG.APV-527 (4-1BBx5T4 bispecific for solid tumors)—plus six preclinical candidates targeting hematologic malignancies and solid tumors.
expected 2026-12-24
| Filed | Period | Accession | Source | Full Text |
|---|---|---|---|---|
| 2026-03-26 | 2025-12-31 | 0001193125-26-126278 | EDGAR | 83K words |
| 2025-02-14 | 2024-12-31 | 0000950170-25-020467 | EDGAR | 83K words |
| 2024-03-05 | 2023-12-31 | 0000950170-24-025428 | EDGAR | 82K words |
| 2023-03-30 | 2022-12-31 | 0000950170-23-010757 | EDGAR | 71K words |
| 2022-03-24 | 2021-12-31 | 0001564590-22-011575 | EDGAR | — |
| 2021-03-31 | 2020-12-31 | 0001564590-21-016875 | EDGAR | — |
| 2020-03-25 | 2019-12-31 | 0001564590-20-012791 | EDGAR | — |
| 2019-03-18 | 2018-12-31 | 0001564590-19-008184 | EDGAR | — |
| 2018-03-13 | 2017-12-31 | 0001564590-18-005384 | EDGAR | — |
| 2017-03-31 | 2016-12-31 | 0001564590-17-005738 | EDGAR | — |
| Filed | Period | Accession | Source | Full Text |
|---|---|---|---|---|
| 2026-08-14 | 2026-06-30 | 0001193125-26-350559 | EDGAR | 46K words |
| 2025-11-06 | 2025-09-30 | 0001193125-25-269598 | EDGAR | 44K words |
| 2025-08-11 | 2025-06-30 | 0000950170-25-106247 | EDGAR | 45K words |
| 2025-05-15 | 2025-03-31 | 0000950170-25-072622 | EDGAR | 42K words |
| 2024-11-07 | 2024-09-30 | 0000950170-24-122837 | EDGAR | 46K words |
| 2024-08-08 | 2024-06-30 | 0000950170-24-093366 | EDGAR | 44K words |
| 2024-05-08 | 2024-03-31 | 0000950170-24-055096 | EDGAR | 41K words |
| 2023-11-14 | 2023-09-30 | 0000950170-23-063379 | EDGAR | 49K words |
| 2023-08-10 | 2023-06-30 | 0000950170-23-040983 | EDGAR | 47K words |
| 2023-05-11 | 2023-03-31 | 0000950170-23-020870 | EDGAR | — |
| 2022-11-10 | 2022-09-30 | 0001564590-22-037287 | EDGAR | — |
| 2022-08-11 | 2022-06-30 | 0001564590-22-029025 | EDGAR | — |
| Filed | Accession | Source | Full Text |
|---|---|---|---|
| 2026-09-24 | 0001193125-26-400213 | EDGAR | 1K words |
| 2026-09-23 | 0001193125-26-399545 | EDGAR | 1K words |
| 2026-09-03 | 0001193125-26-381098 | EDGAR | 1K words |
| 2026-08-21 | 0001193125-26-361079 | EDGAR | 1K words |
| 2026-08-14 | 0001193125-26-350537 | EDGAR | 2K words |
| 2026-08-13 | 0001193125-26-349380 | EDGAR | 1K words |
| 2026-07-27 | 0001193125-26-318056 | EDGAR | 1K words |
| 2026-03-26 | 0001193125-26-126190 | EDGAR | 3K words |
| 2026-03-11 | 0001193125-26-100539 | EDGAR | 2K words |
| 2026-02-19 | 0001193125-26-057707 | EDGAR | 1K words |
255 total filings indexed. 223 additional filings (S-1, DEF 14A, etc.) View all (JSON) · SEC EDGAR
| CIK | 0001671584 |
| Ticker | APVO |
| Exchange | Nasdaq |
| SIC | 2834: Pharmaceutical Preparations |
| Incorporated | DE |
| Website | https://www.aptevotherapeutics.com |
| Listed | 2016-07-20 |
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