Polaryx Therapeutics, Inc.

PLYX · Nasdaq · SIC 2834: Pharmaceutical Preparations · Market Cap: $0.2B
4
SEC Filings
$3.27
Close 2026-05-29

Business Summary

Polaryx Therapeutics is a clinical-stage biotechnology company developing novel disease-modifying therapies for rare, pediatric lysosomal storage diseases (LSDs). Its pipeline includes PLX-200 (gemfibrozil, oral small molecule), PLX-300 (cinnamic acid), PLX-100 (combination therapy), and PLX-400 (gene therapy). Lead candidate PLX-200 is advancing through a Phase 2 basket trial (SOTERIA) targeting CLN2, CLN3, Krabbe disease, and Sandhoff disease, with an FDA-cleared IND received in October 2025.

Latest Stock Quote

PLYX 2026-05-29 $3.27 O:$3.32 H:$3.6497 L:$3.07 Vol:0.6M VWAP:$3.3756
origin leaf: 924353fe7304268f4204a98ff50fc58eb985875061359e41895f1cfba906fdc0

Annual Reports (10-K)

FiledPeriodAccessionSourceFull Text
2026-03-242025-12-310001213900-26-033064EDGAR102K words

Quarterly Reports (10-Q)

No 10-Q filings indexed.

4 total filings indexed. 3 additional filings (S-1, DEF 14A, etc.) View all (JSON) · SEC EDGAR

Sector Peers

SXTP — 60 DEGREES PHARMACEUTICALS, INC. ABT — ABBOTT LABORATORIES ABEO — ABEONA THERAPEUTICS INC. ABVC — ABVC BIOPHARMA, INC. ACAD — ACADIA PHARMACEUTICALS INC ACTU — ACTUATE THERAPEUTICS, INC. ADCT — ADC Therapeutics SA ADIL — ADIAL PHARMACEUTICALS, INC.

Tags

rare-pediatric-lysosomal-storage-diseases-(lsds) neuronal-ceroid-lipofuscinoses-(ncls) krabbe-disease gm2-gangliosidoses-(tay-sachs-and-sandhoff-diseases) niemann-pick-disease-types-a-and-b orphan/rare-disease-therapeutics 505(b)(2)-regulatory-pathway ppar-dependent-upregulation-of-tfeb lysosomal-biogenesis-via-tfeb-activation pi3k-pathway-activation

Company Identity

CIK0002075320
TickerPLYX
ExchangeNasdaq
SIC2834: Pharmaceutical Preparations
IncorporatedWY
Websitehttps://www.polaryx.com
Listed2026-02-02

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