Polaryx Therapeutics is a clinical-stage biotechnology company developing novel disease-modifying therapies for rare, pediatric lysosomal storage diseases (LSDs). Its pipeline includes PLX-200 (gemfibrozil, oral small molecule), PLX-300 (cinnamic acid), PLX-100 (combination therapy), and PLX-400 (gene therapy). Lead candidate PLX-200 is advancing through a Phase 2 basket trial (SOTERIA) targeting CLN2, CLN3, Krabbe disease, and Sandhoff disease, with an FDA-cleared IND received in October 2025.
| Type | Subject | Detail | Quarter |
|---|---|---|---|
| topic_mention | PLYX | discussed_in_filing Artificial Intelligence | |
| topic_mention | PLYX | discussed_in_filing Cybersecurity | |
| topic_mention | PLYX | discussed_in_filing Trusted Computing | |
| topic_mention | PLYX | discussed_in_filing Blockchain & Crypto | |
| topic_mention | PLYX | discussed_in_filing Capital Expenditure | |
| topic_mention | PLYX | discussed_in_filing Regulation | |
| topic_mention | PLYX | discussed_in_filing Healthcare & Bio | |
| topic_mention | PLYX | discussed_in_filing Artificial Intelligence | |
| topic_mention | PLYX | discussed_in_filing Cybersecurity | |
| topic_mention | PLYX | discussed_in_filing Trusted Computing | |
| topic_mention | PLYX | discussed_in_filing Blockchain & Crypto | |
| topic_mention | PLYX | discussed_in_filing Capital Expenditure | |
| topic_mention | PLYX | discussed_in_filing Regulation | |
| topic_mention | PLYX | discussed_in_filing Healthcare & Bio | |
| topic_mention | PLYX | discussed_in_filing Artificial Intelligence | |
| topic_mention | PLYX | discussed_in_filing Cybersecurity | |
| topic_mention | PLYX | discussed_in_filing Trusted Computing | |
| topic_mention | PLYX | discussed_in_filing Blockchain & Crypto | |
| topic_mention | PLYX | discussed_in_filing Capital Expenditure | |
| topic_mention | PLYX | discussed_in_filing Regulation |
| Filed | Period | Accession | Source | Full Text |
|---|---|---|---|---|
| 2026-03-24 | 2025-12-31 | 0001213900-26-033064 | EDGAR | 102K words |
No 10-Q filings indexed.
4 total filings indexed. 3 additional filings (S-1, DEF 14A, etc.) View all (JSON) · SEC EDGAR
| CIK | 0002075320 |
| Ticker | PLYX |
| Exchange | Nasdaq |
| SIC | 2834: Pharmaceutical Preparations |
| Incorporated | WY |
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