Polaryx Therapeutics, Inc.

PLYX · Nasdaq · SIC 2834: Pharmaceutical Preparations · Market Cap: $0.2B
9
SEC Filings
$2
Close 2026-09-04

Business Summary

Polaryx Therapeutics is a clinical-stage biotechnology company developing novel disease-modifying therapies for rare, pediatric lysosomal storage diseases (LSDs). Its pipeline includes PLX-200 (gemfibrozil, oral small molecule), PLX-300 (cinnamic acid), PLX-100 (combination therapy), and PLX-400 (gene therapy). Lead candidate PLX-200 is advancing through a Phase 2 basket trial (SOTERIA) targeting CLN2, CLN3, Krabbe disease, and Sandhoff disease, with an FDA-cleared IND received in October 2025.

Latest Stock Quote

PLYX 2026-09-04 $2 O:$2 H:$2.05 L:$1.9 Vol:0.0M VWAP:$1.971
origin leaf: null

Annual Reports (10-K)

FiledPeriodAccessionSourceFull Text
2026-03-242025-12-310001213900-26-033064EDGAR102K words

Quarterly Reports (10-Q)

FiledPeriodAccessionSourceFull Text
2026-08-132026-06-300001213900-26-089118EDGAR18K words

Recent Current Reports (8-K)

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2026-09-140001213900-26-099416EDGAR1K words
2026-09-010001213900-26-096235EDGAR1K words
2026-07-210001213900-26-080041EDGAR1K words
2026-07-170001213900-26-078912EDGAR1K words

9 total filings indexed. 3 additional filings (S-1, DEF 14A, etc.) View all (JSON) · SEC EDGAR

Sector Peers

SXTP — 60 DEGREES PHARMACEUTICALS, INC. ABT — ABBOTT LABORATORIES ABEO — ABEONA THERAPEUTICS INC. ABVC — ABVC BIOPHARMA, INC. ACIU — AC Immune SA ACAD — ACADIA PHARMACEUTICALS INC ACTU — ACTUATE THERAPEUTICS, INC. ADCT — ADC Therapeutics SA

Tags

rare-pediatric-lysosomal-storage-diseases-(lsds) neuronal-ceroid-lipofuscinoses-(ncls) krabbe-disease gm2-gangliosidoses-(tay-sachs-and-sandhoff-diseases) niemann-pick-disease-types-a-and-b orphan/rare-disease-therapeutics 505(b)(2)-regulatory-pathway ppar-dependent-upregulation-of-tfeb lysosomal-biogenesis-via-tfeb-activation pi3k-pathway-activation

Company Identity

CIK0002075320
TickerPLYX
ExchangeNasdaq
SIC2834: Pharmaceutical Preparations
IncorporatedWY
Websitehttps://www.polaryx.com
Listed2026-02-02

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JSON Profile Stock Quote Origin Record
Origin Provenance
page leaf: a2dc3b5f0e1215a595298e652b5764bdcb7010296c4361a9c1458ea51508734e
parent: 69738cc266a2fa4c2b8a3ad513e42f2379f2d284e7ba8faa01ae44f62c8abd20
content hash: d40304a4a5b27f42cd292f69b251a4ecd343d4ed4176f849568b38ccdeb85b5b
signed: 2026-09-29T19:02:43.659Z
sources: 2 verified data leaves
chain: SEC.gov PEM → origin.rootz.global extraction → this page
verify: sha256(content_hash + parent + timestamp) = leaf

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