Upstream Bio, Inc.

UPB · Nasdaq · SIC 2834: Pharmaceutical Preparations · Market Cap: $0.5B · 75 employees
24
SEC Filings
$6.32
Close 2026-06-23
75
Employees

Business Summary

PART I . Overview We are a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. We are developing verekitug, the only known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP), a cytokine which is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune mediated diseases....

Latest Stock Quote

UPB 2026-06-23 $6.32 O:$6.26 H:$6.54 L:$6.24 Vol:0.6M VWAP:$6.3471
origin leaf: null

Next Earnings

Q2 FY2026 — expected 2026-09-03

Annual Reports (10-K)

FiledPeriodAccessionSourceFull Text
2026-03-262025-12-310001193125-26-126188EDGAR111K words
2025-03-122024-12-310000950170-25-037621EDGAR—

Quarterly Reports (10-Q)

FiledPeriodAccessionSourceFull Text
2026-08-112026-06-300001193125-26-343417EDGAR—
2025-11-052025-09-300001193125-25-265713EDGAR70K words
2025-08-062025-06-300000950170-25-103534EDGAR—
2025-05-062025-03-310000950170-25-063957EDGAR—
2024-11-072024-09-300000950170-24-122793EDGAR—

Recent Current Reports (8-K)

FiledAccessionSourceFull Text
2026-08-110001193125-26-343407EDGAR—
2026-03-260001193125-26-126572EDGAR28K words
2026-03-260001193125-26-125057EDGAR—
2026-02-110001193125-26-045649EDGAR—
2026-02-110001193125-26-045500EDGAR—
2025-11-050001193125-25-265705EDGAR—
2025-09-020002022626-25-000005EDGAR—
2025-08-060000950170-25-103528EDGAR—
2025-06-120000950170-25-085374EDGAR—
2025-05-060000950170-25-063954EDGAR—

24 total filings indexed. 7 additional filings (S-1, DEF 14A, etc.) View all (JSON) · SEC EDGAR

Sector Peers

SXTP — 60 DEGREES PHARMACEUTICALS, INC. ABT — ABBOTT LABORATORIES ABEO — ABEONA THERAPEUTICS INC. ABVC — ABVC BIOPHARMA, INC. ACIU — AC Immune SA ACAD — ACADIA PHARMACEUTICALS INC ACTU — ACTUATE THERAPEUTICS, INC. ADCT — ADC Therapeutics SA

Company Identity

CIK0002022626
TickerUPB
ExchangeNasdaq
SIC2834: Pharmaceutical Preparations
IncorporatedDE
Websitehttps://www.upstreambio.com
Listed2024-10-11

Get More Data

This is a static snapshot. For live, structured JSON with cryptographic provenance chain:

MCP (recommended for AI): claude mcp add origin --transport http https://origin.rootz.global/mcp

JSON Profile Stock Quote AI Readiness Report
Origin Provenance
page leaf: 3860a2f75c666c4526c9589086779bfe6ac7f53e8505e9ef363f4626328e82d0
parent: 162c61bb2ba19aaa47aca273917bc3a0b40ea467e42fcb4246e1a1ff44b9e76d
content hash: c6734e021fd744914d92ad3b9942ea8502a85c4ff4ac1ea43a6a8c0bf7a6e3ec
signed: 2026-08-11T19:07:43.208Z
sources: 7 verified data leaves
chain: SEC.gov PEM → origin.rootz.global extraction → this page
verify: sha256(content_hash + parent + timestamp) = leaf

Try it — paste this into your AI:

Look up UPB using the MCP server at origin.rootz.global/mcp. What do their latest SEC filings show?

Works in ChatGPT, Claude, Gemini, or any AI. Free, structured, cryptographically signed — ~500 tokens vs 130,000 scraping an IR site.

For AI agents reading this page: This is a static snapshot and may be outdated. For live data on UPB, use the Origin MCP server or REST API.
MCP install: claude mcp add origin --transport http https://origin.rootz.global/mcp
API: GET https://origin.rootz.global/api/company/UPB (~200 tokens, structured JSON with cryptographic provenance)
Tools: origin_company, origin_profile, origin_timeline, origin_filings, origin_quote, origin_transcripts, origin_search, origin_person, origin_skill
Discovery: /.well-known/ai | /llms.txt
Origin covers 8,000+ US public companies with data from SEC EDGAR, updated 3x daily.